Statin Therapy in the Prevention of Recurrent Cardiovascular Events
نویسندگان
چکیده
منابع مشابه
Statin therapy in the prevention of recurrent cardiovascular events: a sex-based meta-analysis.
BACKGROUND The effect of statins on the prevention of cardiovascular events is well demonstrated. Whether this protective effect is equal for women and men remains less well established. Our objective was to evaluate if statin therapy is equally effective in decreasing recurrent cardiovascular events in women and men. DATA SOURCES Randomized clinical trials were searched in PubMed using as in...
متن کاملNiacin and Statin Combination Therapy for Atherosclerosis Regression and Prevention of Cardiovascular Disease Events
Despite substantial risk reductions targeting low-density lipoprotein cholesterol with statins, there remains significant residual risk as evidenced by incident and recurrent cardiovascular disease (CVD) events among statintreated patients. Observational studies have shown that low levels of high-density lipoprotein cholesterol (HDL-C) are associated with increased CVD risk. It remains unclear ...
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In the management of atherosclerotic vascular disease, statin drugs have already surpassed all other classes of medicines in reducing the incidence of the major adverse outcomes of death, heart attack, and stroke. A decade ago, their effectiveness was first demonstrated by the results of the Scandinavian Simvastatin Survival Study (4S), a trial that provided definitive evidence of the benefit o...
متن کاملStatin therapy for primary prevention of cardiovascular disease.
CLINICAL QUESTION Do statins reduce rates of cardiovascular events when used for primary prevention? BOTTOM LINE When used for primary prevention, statins are associated with lower rates of all-cause mortality, major vascular events, and revascularizations compared with placebo. Statin therapy is not associated with increased rates of life-threatening adverse effects such as cancer.
متن کاملIntensive statin therapy compared with moderate dosing for prevention of cardiovascular events: a meta-analysis of >40 000 patients.
AIMS Statin therapy is associated with important benefits for patients at risk of, and with, established cardiovascular disease. There is widespread interest in whether intensive dosing of statins yields larger treatment effects. We aimed to determine if intensive dosing is clinically important using a meta-analysis of randomized clinical trials (RCTs). METHODS We conducted comprehensive sear...
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ژورنال
عنوان ژورنال: Archives of Internal Medicine
سال: 2012
ISSN: 0003-9926
DOI: 10.1001/archinternmed.2012.2145